Which AI model scores highest on BioMysteryBench?

Claude Opus 5 by Anthropic holds the best BioMysteryBench (human solved) result among tracked models, at 90.1% (released Jul 24 2026). Higher scores are better on this benchmark.

What are the top 3 models on BioMysteryBench?

1. Claude Opus 5 (Anthropic) — 90.1%; 2. Gemini 3.8 Flash (Google) — 88.8%; 3. Gemini 3.7 Flash (Google) — 87.1%.

How many models have a published BioMysteryBench score?

3 tracked models have a published BioMysteryBench (human solved) score. Scores are the figures reported by each lab at that model's release, so this page is a record of results over time rather than a re-run leaderboard.

Biology

BioMysteryBenchhuman solved

Real biology puzzles that human experts have managed to crack — can the AI reach the same answers? Higher is better.

hard human solved

Rankings

Higher is better

BioMysteryBench — frequently asked questions

: Real biology puzzles that human experts have managed to crack — can the AI reach the same answers? Higher is better.
: Claude Opus 5 by Anthropic holds the best BioMysteryBench (human solved) result among tracked models, at 90.1% (released Jul 24 2026). Higher scores are better on this benchmark.
: 1. Claude Opus 5 (Anthropic) — 90.1%; 2. Gemini 3.8 Flash (Google) — 88.8%; 3. Gemini 3.7 Flash (Google) — 87.1%.
: 3 tracked models have a published BioMysteryBench (human solved) score. Scores are the figures reported by each lab at that model's release, so this page is a record of results over time rather than a re-run leaderboard.