Mixtral 8×22B and o4-mini-high don't publish scores on any of the same benchmarks, so there's no direct head-to-head comparison. Mixtral 8×22B shipped 371 days before o4-mini-high, so benchmark comparisons should account for the intervening progress.

Mixtral 8×22B is open weight, while o4-mini-high is proprietary.

Direct benchmark comparisons are unavailable — Mixtral 8×22B and o4-mini-high don't publish scores on any of the same benchmarks.