Mixtral 8×22B and GPT-5.6 Luna don't publish scores on any of the same benchmarks, so there's no direct head-to-head comparison. Mixtral 8×22B shipped 807 days before GPT-5.6 Luna, so benchmark comparisons should account for the intervening progress.

Mixtral 8×22B is open weight, while GPT-5.6 Luna is proprietary.

Direct benchmark comparisons are unavailable — Mixtral 8×22B and GPT-5.6 Luna don't publish scores on any of the same benchmarks.